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Sulfasalazine (SAS) also acts on System X C - to inhibit the uptake of cystine [149], causing chronic depletion of glutathione in cells, thereby destroying the redox defense of cells, hindering tumor growth, and inducing tumors ferroptosis [149,150,151,152,153]

Blood pressure recordings were performed by the Telemetry Unit for Cardiovascular Phenotyping at the University of Copenhagen, supported by the Novo Nordisk Foundation (grant number NNF18OC0032728 to M.B.T.)

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10.1097/cm9.0000000000000627 55 YaoJ.ZhaoL.ZhaoQ.ZhaoY.SunY.ZhangY.et al (2014)