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The most commonly reported side effects in clinical trials are nausea, vomiting, diarrhoea, and constipation consistent with the gastrointestinal effects seen with GLP-1 monotherapy

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Oral Bioavailability: A Notable Advantage The poor bioavailability of oral peptide incretins has historically been a major limitation, primarily due to digestive enzyme hydrolysis in the GI tract and low permeability of intestinal epithelial cells

Weight loss while taking psyllium husk may occur more rapidly if combined with daily physical activity and a healthy diet