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Description

Four dogs with spontaneous cancer were used to test the anti-tumor effects of nitrosylcobalamin (NO-Cbl), a vitamin B12-based carrier of nitric oxide (NO) that induces apoptosis

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doi: 10.1016/j.ccr.2011.11.002 104 LeblancRLeeSCDavidMBordetJCNormanDDPatilRet al

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Activated caspase-4/5/11 cleaves GSDMD, with its N-terminal fragment forming membrane pores, leading to pyroptosis

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