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Take home message Three oral GLP-1 medications are relevant to UK consumers in 2026

Oxidized forms notably include disulfides, either with another glutathione cysteine residue to produce glutathione disulfide (GSSG) or with a different thiol to form mixed disulfides, as well as more oxidized forms in which the thiol group is converted to sulfenic, sulfinic or sulfonic acids (Foyer and Noctor, 2005)

3), which provides a mechanistic insight into the use of combination treatment including incretin-based therapy for type 2 diabetes

3) Fatty acid attached to C-terminus of peptide via linker to promote albumin binding with or without GLP-1R binding