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Available from: Next scheduled review date: 29 December 2028 More on this topic What Is Off-Label Prescribing

doi: 10.1093/nar/gkx1089 105 BranisteVAl-AsmakhMKowalCAnuarFAbbaspourATthMet al

Srensen MB, Rosenfalck AM, Hjgaard L, Ottesen B

The potent TGR5 agonist 6-ethyl-23(S)-methylcholic acid (INT-777) inhibits inflammation in macrophages through TGR5-mediated targeting of cAMP and NF-B signaling pathways (117)