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These medications may increase the risk of inflammation in the pancreas

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In summary, GLP-1RAs have the potential to inhibit neuroinflammation and promote nerve regeneration through the "Tregs-microglia-neuron/NPCs" axis: (1) GLP-1RAs directly and indirectly inhibit the activation of microglia, promote their M2 polarization, and secrete cytokines such as IL-4, IL-10, TGF - , IL-2 to exert anti-inflammatory effects (100)

Contact your GP if fatigue is severe, significantly impairs daily functioning, persists despite self-management strategies, or is accompanied by signs of dehydration, hypoglycaemia, persistent vomiting, or symptoms suggesting nutritional deficiency such as pale skin or muscle weakness