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30 Once the ox-LDL particle has disrupted the integrity of the endothelial barrier, additional LDL particles flood into the arterial wall (intima)
A class of peptic ulcer and antacid drugs called histamine H2 receptor agonists, including Tagamet, Zantac, and Pepcid Anticonvulsants including phenobarbital, primidone, and phenytoin Bile acid sequestrants including colestipol and cholestyramine, which lower cholesterol Chemotherapy medications like methotrexate Metformin, which is a diabetes drug Proton pump inhibitor drugs used to treat acid reflux, such as omeprazole (Prilosec), esomeprazole (Nexium), or lansoprazole (Prevacid) Tetracycline, an antibiotic Lastly, it is also essential that you communicate with your provider if you have kidney disease or an allergy to cobalt or any other medication, vitamin, dye, food, or preservative
Splitting the dose or adding a second daily injection is not part of the clinical protocol and may not improve outcomes
More significant changes in thickness and density are typically seen after 36 months of consistent use
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