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Ahmad J, Hamdy AM, Elfakharany B, et al

It's produced by enteroendocrine L-cells that line your small and large intestine

In addition to this the presence of antibodies which cross-react with host dsDNA and antigens of the gut commensal Ruminococcus gnavus in SLE patients further implies that microbial translocation contributes to disease development and/or progression (Azzouz et al