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OZEMPIC (semaglutide) injection is used to help lower blood sugar levels in people with type 2 diabetes

They found that the indole-based molecules have superiority over previously tested inhibitors

In addition to the well-known effects of GLP-1 and GLP-1 RA in improving insulin sensitivity and reducing body weight, at central levels, GLP-1 and GLP-1 RA might exert regulating effects on GhRH release, and on concomitant gonadotropin secretion, likely by activating the kisspeptin hypothalamic system, a key regulator of the pulsatile release of GnRH from GnRH neurons

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