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For example, SBP reductions were only 1.2 mmHg in the LEADER study and 1.7 mmHg in the REWIND study (54, 67), yet, the GLP-1RAmediated reduction in ASCVD reduction was comparable to that observed in the other CVOTs (48)

Its only really present in just the last three years and its a bit early, I think, to draw any firm conclusions

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For patients who stayed on the treatment, reduced their calorie intake and exercised, Novo Nordisk estimates they would have a 16.6% reduction in their weight