glp-1 cirrhosis The treatment of diabetes mellitus of patients with chronic liver disease GLP-1 Drugs May Trigger Muscle

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Diabetes & Primary Care

Glucagon receptor agonism in isolation raises blood glucose which is why glucagon was historically viewed as problematic in metabolic disease but when co-activated alongside GLP-1 and GIP signaling, the glucose-raising effect is offset while the energy-expenditure effect is preserved

This can be even worse following a workout as your body will have produced stress hormones that will keep you awake, so, paired together, theres a real risk of not being able to fall asleep