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Immune Senescence and Thymic Biology Age-related immune decline (immunosenescence) involves thymic involution, reduced naive T-cell output, and accumulation of terminally differentiated effector-memory cells

BPC-157 (Sikiric et al., 2014): Angiogenesis driver through VEGF and nitric oxide modulation

as such, the cohort entry could be constructed based on prescription dates, a lookback window could be used to define pre-exposure eligibility and covariates, and the date of outcomes could be ascertained