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That dose-response pattern is exactly why the trials tested several target levels instead of pushing everyone to the maximum: some people reach their goals at a lower dose with fewer side effects
Identification and Characterization of a Pi Isoform of Glutathione S-Transferase (GSTP1) as a Zeaxanthin-Binding Protein in the Macula of the Human Eye
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Mohs excision has also been used for treatment of melanoma in situ, but even with Mohs excision clear margins are still uncertain due to difficulty of seeing atypical melanocytes on frozen sections
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