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In a 12-month study of 339 Second Nature members published in JMIR Formative Research, participants on tirzepatide lost an average of 22.1% of their body weight, and those on semaglutide lost 17.1% 11

At 5 mg/ml concentration: 0.25 mg = 0.05 ml = 5 units

The lack of clear labeling and variability in individual sensitivities can make selecting supplements daunting

Both the Kidney Disease Improving Global Outcomes guidelines and American Diabetes Association Standards of Care recommend GLP1-RA as the preferred glucose lowering class for people with T2D and moderate to advanced CKD or ESRD because of their demonstrated cardiovascular benefits in people with T2D at high risk of cardiovascular disease, which includes CKD 13,14