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Results Post hoc epigenetic age analysis of a randomized trial of semaglutide To determine whether semaglutide treatment could impact biological aging, we conducted a post hoc epigenetic analysis of participants enrolled in a previously reported 32-week, randomized, double-blind, placebo-controlled phase 2b clinical trial (NCT04019197) evaluating semaglutide in PWH and lipohypertrophy 19 (Fig

GLP-1 Receptor signaling in astrocytes regulates fatty acid oxidation, mitochondrial integrity, and function