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LC3-I, Microtubule-associated proteins light chain 3-I

The expression level and activity of SP1 are often abnormally elevated in lung cancer tissues, and its high expression is significantly associated with a poor prognosis ( 2.7.2 Naamidine J inhibits the nuclear translocation of SP1 by targeting CSE1L to slow down lung injury Naamidine J (NJ) is a marine alkaloid and has been identified as a specific inhibitor of the nuclear transport protein CSE1L through chemical proteomics technology

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While many tumor cells exhibit the Warburg effect, 260 which favors aerobic glycolysis, the metabolic profiles of CSCs are far more diverse and adaptive, often reflecting the unique demands of maintaining a stem-like state in microenvironments