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Salcedo I, et al

This depends entirely on your research protocols dosing requirements

In recent years, with the increasing resolution of the ASCT2 3D structure, cysteine residue C467 is an important part of the composition of the ASCT2 substrate binding site, and residue C467 plays a key role in recognizing and binding glutamine [176]

While glutathione may not "remove" melasma in the sense of a one-time treatment, its ability to inhibit dark pigment production and shift the body toward a brighter tone makes it a valuable ally