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Front Biosci (Schol Ed) 3:12161231 Gu Y, Zheng G, Xu M, Li Y, Chen X, Zhu W, Tong Y, Chung SK et al (2012) Caveolin-1 regulates nitric oxide-mediated matrix metalloproteinases activity and bloodbrain barrier permeability in focal cerebral ischemia and reperfusion injury

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Hesperidin (Matias et al., 2017), rutin (Omar et al., 2017) can reduce the amount of free Ca 2+ located between brain cells when fighting against neurogenic excitotoxicity and can attenuate the decrease of the mitochondrial membrane potential and increase caspase-3 activity (Lutz et al., 2015)