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Guided by many promising preclinical studies that potentially link GSH and oxidative stress with the pathophysiology of SZ, multiple groups have also conducted clinical studies and measured GSH levels in peripheral blood of patients with SZ

Collectively, these treatment approaches focus on eliminating infection, immunomodulation, mechanical ventilation, and removal of malignant tissue (surgical interventions)

These bacterial substances include lipoproteins and endotoxins, which cause a surge in inflammatory cytokines like tumor necrosis factor (TNF-) and interleukin-6 3 5

The newer drugs have fewer side effects and superior pharmacokinetic profiles