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The tolerogenic mechanism is elegant: by presenting histone epitopes in a context that promotes regulatory rather than effector T cell responses, these peptides essentially re-educate the immune system to tolerate its own nuclear components

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This helps regulate blood sugar levels and reduces appetite which helps with weight loss

Because glutamine/glutamate and cysteine metabolic pathways are deeply connected (130, 131) and cysteine is also considered a modulator of glutamine transport (132, 133), certainly these transporters are crucial in the cysteine metabolism reliance of cancer cells