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Description

Deficits in these reward processes are often inappropriately labeled under the umbrella of anhedonia

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This triggers broken immune tolerance: Overactivated innate immune cells secrete pro-inflammatory cytokines, CD4 + T cells skew toward pro-inflammatory subsets (T-helper 1 [Th1] cells/Th17), T regulatory cell (Treg) function is impaired, and autoantibodies exacerbate inflammation

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It improves insulin sensitivity. Glucose and insulin measurements changed in diet-induced obese mice

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