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re-evaluate weight trajectory at 12 and 24 weeks Renal function annually or if patient reports persistent nausea and decreased oral intake Thyroid exam if the patient reports neck fullness or dysphagia (both carry a boxed warning for medullary thyroid carcinoma risk in patients with a personal or family history of MEN2) GLP-1-associated pancreatitis is rare (observed rate approximately 0.1 to 0.3 per 100 patient-years across trials) but requires vigilance

2-5L) was injected through the ICV infusion needle

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