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By starting with a low dose and incrementally increasing it over several weeks or months, your body has time to acclimate, which improves tolerability and helps ensure you can continue treatment effectively towards a maintenance dose

While this sensation is harmless and does not mean the medication isnt working, it can contribute to needle anxiety. Bolded Lead Sentence: Removing the chill from the medication allows the liquid to enter the subcutaneous tissue (the fat layer just under the skin) more gently

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