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One common side effect of statins is muscle pain, and some research correlates statin use and a deficiency in CoQ10.6 A targeted study from 2025 revealed that a daily 200mg dose of CoQ10 could significantly reduce statin-related muscle pain.28 Additional research showed 100mg of CoQ10 supplementation could reduce symptoms of mitochondrial dysfunction brought on by statin use.7 Oxidative stress A systematic review and meta-analysis of papers looking at oxidative stress in athletes found that doses less than or equal to 300mg per day successfully reduced markers of oxidative stress after bouts of exercise