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In LOsG-induced prediabetes, although pancreatic ROS stress remained high on LOsG treatment day 38, there were no alterations in mRNA levels of ER stress (XBP1 and BIP), inflammation (IL6 and IL1), and hypoxia-responsive (HIF1 and GAPDH) genes between LOsG- and sham-treated groups

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NGAL, neutrophil gelatinase-associated lipocalin

We also detected increased recruitment of the mitochondrial fission protein mCherry-Drp1 to mito-BFP-expressing mitochondria in exendin-4-stimulated versus vehicle-exposed WT INS-1 832/3 cells (Fig