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The clinical pictures of vitamin B12 allergy caused by type 1 hypersensitivity that have been revealed with basophile histamine release test and skin prick tests as we have performed in our patient.10 We did not perform basophile histamine release test or specific IgE determination to indicate type 1 hypersensitivity reaction because of positive SPT results of both types of cobalamin preparation

Vitamin B12 Injection Dosage and Administration Guidelines Typical dosing starts with frequent injectionsoften daily or weeklyto replenish stores, followed by maintenance doses monthly or bi-monthly

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However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc