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3.4 Methylene blue demonstrated low cytotoxicity to PBMCs but higher to the hepatocarcinoma cell line HepG2 In order to evaluate whether the MB concentrations used in the assays are cytotoxic, cell viability assays were carried out

Wang G, Liu X, Meng L, Liu S, Wang L, Li J, Cui C, Meng J, Hu S, Wei Y

Bilirubin nanomedicine ameliorates the progression of experimental autoimmune encephalomyelitis by modulating dendritic cells

Moreover, a double-blind, placebo-controlled trial revealed that in the chronic hepatitis C patients with vitamin D levels less than 30 ng/mL treated with vitamin D supplements for 6 weeks, the mean 25(OH)D level in vitamin D group was significantly increased and normalized, and the serum CXCL10 levels were decreased significantly as compare to the placebo group