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70 Various strategies for lowering lipids, such as physical activity, weight loss and bariatric surgery, have been reported to have positive effects, but the use of lipid-lowering medicine does not seem to be effective at slowing the development of DN

Microbiome The multiple interactions among tumor microenvironment, microbiome, host factors, and response to ICI, and the development of ICI-associated irAEs are largely unknown (101)