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*Correspondence: Mahdyieh Naziri, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The activated lipase breaks down stored triglycerides into free fatty acids that can be released into the bloodstream and oxidized for energy

Not for injection into humans or animals

Rapamycin-induced autophagy ameliorates GSH depletion-induced premature cell senescence It was shown that autophagy activation especially in the presence of an increasing autophagic flux inhibits the senescence of RPE cells 35,36,37,38,39