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Key Pathobiology Relevant to Regeneration Disc dehydration, inflammation, and matrix breakdown are central pathological processes in lumbar disc degeneration (LDD), each critically influencing the potential for regeneration and the efficacy of emerging biologic therapies

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Best for: Systemic applications or multiple injury sites where broad distribution is desired Option C: Separated Sessions Sequence: BPC-157 in morning, cryotherapy in evening (or vice versa) Rationale: Eliminates potential interaction effects by separating the modalities entirely