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Therefore, anti-inflammatory and neuroprotection effects might be exerted through inhibiting NF-B and MAPKs signaling pathways (88)

Our study supports the efficacy of GLP-1 RAs in reducing cardiovascular events among individuals with concurrent type 2 diabetes and AKD, highlighting their role in the complex management of these comorbid conditions

Unfortunately, evidence 31 shows that drastic and rapid weight losswhether from GLP-1 RA use, bariatric surgery, or diet-induced methodscan reduce LBM by up to 50% of the total weight lost