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Understanding an individual's genetic, dietary, and microbiome profiles could improve the effectiveness of these interventions and minimize the potential adverse effects of these treatments

Obesity, particularly central or abdominal obesity, increases insulin resistance, thereby making it difficult for the body to regulate blood sugar levels

If you weigh 250 pounds, semaglutide could result in 37-55 pounds of weight loss versus 5-7 pounds with metformin alone, demonstrating semaglutide's substantially greater effectiveness for weight reduction

The exact dosage and timing depend on what your doctor prescribes, but in most cases you take it once a day, either before or after breakfast