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Description

Conclusions These findings demonstrate that celastrol alleviates DKD-associated renal injury by inhibiting ferroptosis via activation of the SIRT1/NRF2/GPX4 signalling pathway

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A recent observational study showed an association of CYP3A5*3 with higher doses in all ancestries, but CYP3A5*6 and CYP3A5*7 were present only in African Americans (117)

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doi: 10.1196/annals.1320.003 15 MorimotoNHashimotoSYamanakaMSatohMNakaokaYFukuiAet al

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