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The Science Behind Hyperbaric Oxygen Therapy: HBOT involves breathing pure oxygen in a pressurized chamber, allowing oxygen to dissolve into the bloodstream at higher concentrations

Therefore, it is essential to understand alternative metabolic pathways and detoxification mechanisms, which may vary based on daily dose and drug-metabolizing enzyme responses, to mitigate the risks of toxicity (Teo et al., 2015)

For the subgroup analysis, the studies were classified based on if the patients from the control group received metformin or placebo