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Ozempics brain effects extend beyond weight management, but most are related to how the drug helps regulate appetite and increase feelings of fullness

By modulating inflammatory responses, GLP-1RAs can help prevent the degeneration of dopamine-producing cells.413 GLP-1RAs play a neuroprotective role in neurons by facilitating neuronal survival and promoting neuronal growth, thereby preserving the structural and functional integrity of synapses.6,14 Furthermore, GLP-1 signaling indirectly enhances and restores the insulin signaling pathway in neurons, leading to a reduction in the phosphorylation of insulin receptor substrates and the burden caused by monomeric -synuclein.414 Together, these effects contribute to the protection of dopaminergic neurons (source)

Contempr B, de Escobar GM, Denef JF, Dumont JE, Many MC

Several are FDA-flagged or WADA-banned