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And its a history with its share of ignominy: In the mid-1990s, a drug that combined fenfluramine and phentermine, known as fen-phen, exploded in popularity after a single, 121-patient study showed it was effective for weight loss

Importantly, both compounded and counterfeit products are often dispensed in multi-dose vials with syringes labeled in units or mg rather than mL, which has led to numerous inadvertent overdoses

What makes knownwell different: Weight-inclusive healthcare designed for all body types Virtual and in-person visits available Primary care alongside weight management services No judgment, blame, or shame in our approach We understand that sustainable weight management requires addressing your whole health story

It is important to distinguish between direct pharmacological effects and indirect consequences of treatment