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why would tirzepatide not work

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Description

Here, we find that semaglutide engages both G s - and G q -dependent signalling pathways in Glp1r -expressing neurons in the area postrema (AP Glp1r ), the primary site of semaglutide action in the brain, and differentially regulates neuronal activation across distinct neuronal clusters

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Handa RK, Ferrario CM, Strandhoy JW

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