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taking with food and earlier in the day can help reduce discomfort or sleep disruption

Biosci Biotechnol Biochem 84(3):463470

Frontiers in Pharmacology, 12, 2021

(Glucagon stimulates the liver to release sugars that have been stored in the bloodstream.) Slows the absorption of glucose into the blood by reducing the speed at which the stomach empties after eating, thus making you feel more satisfied or extending the sensation of feeling full after a meal