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The GSH/GSSG ratio serves as a primary determinant of the cellular redox state, as reduced GSH is thought to repair oxidative damage to protein thiols and to support redox signaling, the regulation of cell proliferation, control of the cell cycle, initiation of apoptosis, modulation ofthe immune response, and maintenance of skin pigmentation
, Selenium supplementation shows protective effects against patulin-induced brain damage in mice via increases in GSH-related enzyme activity and expression, Life Sci
They together help keep glutathione at optimal levels, plus boost our immune systems and overall body function
In ME/CFS, SNPs in TLR signalling pathways, the complement cascade, and cytokines have been identified (74, 496)
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