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Certain patients, such as those with a hereditary eye condition called Lebers disease, should avoid B12 injections altogether, as these may worsen symptoms

As well, some people may have allergies or medical conditions that do not allow them to be a good candidate to receive vitamin B12 shots, such as kidney problems, low potassium levels, deficiencies in other vitamins such as iron or folic acid, or just an allergy or sensitivity to vitamin B12 itself

The regulations which include GMP Good Manufacturing Practice and additional requirements protect the product through maintaining its safety and purity and effectiveness