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Patients who push through the first four to eight weeks of treatment, with appropriate management of their symptoms, typically find that side effects improve substantially even as the dose continues to increase

Comparisons with single and dual agonists have become a key area of discussion in the literature

Its very much like were building the plane while flying it. In fact, some of those newer benefits werent even included in their models because the data came out after their analysis was complete

During the first 24 weeks, you may experience: Nausea (the most frequently reported side effect, affecting 20-40% of patients initially, varying by product and dose according to SmPC data) [20] [17] Reduced appetite or early satiety Occasional vomiting Mild abdominal discomfort or bloating Changes in bowel habits, including constipation or diarrhoea These effects typically diminish as your body adjusts to the medication, usually within 48 weeks