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FIGURE 4 6 Novel strategies targeting estrogen signaling and/or biosynthesis for skin wound healing 6.1 Selective estrogen receptor modulators Recent studies have tested natural and engineered selective estrogen receptor modulators (SERMs) to increase estrogen signaling in non-healing wounds of elderly patients without systemic side effects (Stevenson and Thornton, 2007

Enabling direct comparison of selective GLP-1R biology versus dual incretin receptor co-agonism to characterise the additive GIPR contributions to metabolic efficacy exceeding Semaglutides GLP-1R-only profile