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doi: 10.1016/j.ecolind.2017.08.052 27

110,111 Preclinical data indicate that SIRT1 activators, such as resveratrol and SRT1720, improve insulin tolerance by activating the AMPK/IRS-1/Akt pathway, inhibiting FOXO1, 112 and downregulating phosphoenolpyruvate carboxykinase and glucose-6-phosphatase expression

Previously published transcriptomic comparisons between the two isogens suggested that AES-1M biofilms differ in structural constituents, with significant upregulation of adhesive polysaccharide, alginate, and other biofilm development genes (25), which may be influencing this result

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