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In the Phase 2 obesity trial it produced about 24% weight loss at 12 mg over 48 weeks, the most of any drug in the class, and it cut liver fat by 86% in the people who started with fatty liver. In the 80-week Phase 3 obesity trial of 2,300 adults with an average BMI of 40, 12 mg produced 28% weight loss and 9 mg reached 26%

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However, results are dose-dependent and more effective when combined with a calorie-controlled diet or exercise program Could Help Prevent Fat Storage (Reduced Lipogenesis) Some animal studies suggest AOD9604 may limit the formation of new fat cells, known as lipogenesis (preclinical evidence)