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Meta-analyses of randomized trials corroborate these findings: one large review of 27 RCTs reported no significant difference in suicidality between GLP-1 RAs and placebo (RR 0.76) [48], while another meta-analysis including 25 trials similarly showed no association across multiple subgroups and endpoints (RR 0.84) [49]

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7, the K8A mutant protein showed significantly reduced DHAR activity

It is made with a prebiotic soluble fiber that is slowly fermented in the large intestine, making it less likely to cause discomfort like bloating or cramping compared to other fibers