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10,23 This mechanism helps prevent severe hepatocellular injury but can result in elevated serum bile salts in addition to conjugated bilirubin, 22 although clinically significant cholestasis is rare

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This mechanism inhibits the acetylation of FoxO1, reduces the levels of TGF-, connective tissue growth factor (CTGF), and the expression of fibrotic markers collagen I and fibronectin, alleviating the degree of fibrosis

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