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Step 1: Concentration = 5 mg / 2 mL = 2.5 mg/mL Step 2: 250 mcg = 0.25 mg Step 3: Volume = 0.25 mg / 2.5 mg/mL = 0.1 mL Step 4: Units = 0.1 mL x 100 = 10 units Draw to the 10-unit mark on your insulin syringe

In SURMOUNT-1 (tirzepatide), about ~25% of the total weight lost was lean mass and ~75% was fat mass over 72 weeks (36)

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Commonly used GLP-1 receptor agonists: Ozempic (semaglutide) Rybelsus (semaglutide) Wegovy (semaglutide) Trulicity (dulaglutide) Victoza (liraglutide) Saxenda (liraglutide) Mounjaro (tirzepatide) Which GLP-1 is best for diabetes