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The FDA withdrew its approval of Lorcaserin in 2020 after studies showed significant cancer occurrence with this drug and disproportionate risks to benefits [35]

References Oral semaglutide: An OASIS from injectables. The Lancet Diabetes & Endocrinology , 2023

Because of this potential concern, individuals with a personal or family history of thyroid cancer or endocrine tumors are generally advised against using semaglutide

The participants of the study also completed patient-reported outcome questionnaires assessed by status scores of the Diabetes Treatment Satisfaction Questionnaire [4]