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Supplementation with oral glutathione may not be beneficial as digestive peptidases degrade it, and several studies show no change in glutathione levels 16 following supplementation

Immunofluorescence staining The mice were deeply anesthetized and then euthanized by cervical dislocation

It inhibits tyrosinase, a key enzyme involved in melanin production, and it also shifts melanin synthesis towards lighter pheomelanin rather than darker eumelanin, contributing to brighter-looking skin. Mechanism of action on pigmentation Melanin is the pigment responsible for skin colour, and its overproduction contributes to tanning, dark spots, and uneven tone

Melasma is essentially a skin mark that is rainbow colored