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The L66 mouse line, which overexpresses the full-length human tau with double mutations (P301S/G335D), demonstrates reduced nest building and sucrose preference at 5-6 months old, suggesting apathy-like deficits (Melis et al., 2015

The number of C-CASP3-positive SGNs was downregulated in the presence of ebselen, while it was further increased in gpx1 / mice compared with the peroxynitrite-only group (Figure 4B)

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